Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus

  • Silva Pavaci | silpavaci@yahoo.it Department of Applied Clinical and Biotechnological Sciences, University of l’Aquila, L'Aquila; Minimally Invasive ENT Surgery Unit, San Carlo di Nancy Hospital, Roma, Italy.
  • Federica Tortorella Department of Applied Clinical and Biotechnological Sciences, University of l’Aquila, L'Aquila; Minimally Invasive ENT Surgery Unit, San Carlo di Nancy Hospital, Roma, Italy.
  • Alessandra Barbara Fioretti Tinnitus Center, European Hospital, Roma, Italy.
  • Anna Maria Angelone Department of Life, Health and Environmental Sciences, University of l’Aquila, Italy.
  • Lino Di Rienzo Businco Minimally Invasive ENT Surgery Unit, San Carlo di Nancy Hospital, Roma, Italy.
  • Maria Lauriello Department of Applied Clinical and Biotechnological Sciences, University of l’Aquila, L'Aquila, Italy.
  • Alberto Eibenstein Department of Applied Clinical and Biotechnological Sciences, University of l’Aquila, L'Aquila, Italy.

Abstract

Tinnitus is defined as perception of a sound without sound stimulation. This study aims to investigate the correlation between chronic tinnitus and the most significant clinical comorbidities and pharmacological treatments. We recruited 130 consecutive outpatients with a tinnitus for least from three months and 100 subjects without tinnitus. All patients had a full medical and audiological evaluation and all filled in Tinnitus Handicap Inventory questionnaire and Khalfa’s Hyperacusis questionnaire. We also analyzed the qualitative variables: audiometry exam, tinnitus characteristics and psychometric questionnaires. Univariate logistic regression was performed to evaluate the associations between the presence of tinnitus and the presence of comorbidities and drug intake. The statistical analysis provided the following results in the group of patients with tinnitus. We obtained an Odds Ratio statistically significant for the following categories taken into consideration: the presence of anxiety and depression, neurological diseases, headache, temporomandibular joint (TMJ) disorders, intake of levothyroxine and proton-pump inhibitor. In this study, we tried to evaluate the audiological characteristics in the subjects affected by chronic tinnitus in order to find a possible correlation with the comorbidities and any drugs intake. We found a statistically significant correlation between tinnitus and comorbidities like anxiety, depression, TMJ disorders, dysthyroidism, headache and levothyroxine and PPI intake.

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Published
2019-12-19
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Original Articles
Keywords:
Tinnitus, comorbidity, drugs medication, levothyroxine, proton-pump inhibitor.
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How to Cite
Pavaci, S., Tortorella, F., Fioretti, A. B., Angelone, A. M., Di Rienzo Businco, L., Lauriello, M., & Eibenstein, A. (2019). Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus. Audiology Research, 9(2). https://doi.org/10.4081/audiores.2019.231